BDBM190666 US10759791, Compound 14h::nNOS inhibitor, 4

SMILES CN1CCC(CC1)c1cncc(CCc2cc(C)cc(N)n2)c1

InChI Key InChIKey=UTFTUBTWHNJKBO-UHFFFAOYSA-N

Data  15 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 190666   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

US Patent
LigandPNGBDBM190666(US10759791, Compound 14h | nNOS inhibitor, 4)
Affinity DataKi:  1.18E+4nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

US Patent
LigandPNGBDBM190666(US10759791, Compound 14h | nNOS inhibitor, 4)
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of recombinant mouse macrophage iNOS expressed in Escherichia coli using L-arginine as substrate assessed as reduction in NO production me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed